Yep. The lifters can be a PITA on the pre 1998 isuzu 3.2's. 1998+ do not have hydraulic valve lash adjusters. These engines use mechanical / solid shim & bucket adjusters. Sbhatcher, are you sure it's not a heat sheild vibrating somewhere? Also, I've seen & driven 5spd manuals (mostly GM truck variants) that rattle a bit in 4th & 5th. Was told that its a idler shaft in the tranny. Have you checked / changed the tranny lube recently?
G/luck
Joel
G/luck
Joel