JTK I don't think the ECU is that smart. I suspect all it knows is that it wants to control/fire to a certain ohm value during the ion sensing voltage pulse. It isn't sensing instantaneous cylinder gas compositions. That work was likely done by GM in a lab. They found the target gas compositions they wanted. They noted what ohm reading that occured at using presumably only the specified spark plugs. Then they pre-programmed that number into the ECU. Thus if you change the plug type (i.e. starting plug resistance) you change when the computer thinks the cylinder should be fired. Again, the ECM is only smart enough to know what the engine electrical readings are. Any change to the inherent plug resistance and the system is compromised. Again just my take and I am certainly no expert in this system so I could no doubt be wrong.
As to when Isuzu went to ion-sensing, IIRC that happened in 2001. 96rodeo you don't have to worry about this. You only have the typical match the plug for your engine concerns (e.g. right dimensions, heat range, gap, etc.).