I have a 98 Amigo and I'm running 285/75 16's right now and I get rubbing when I turn with out even hitting a bump. On Monday I'm taking it in to an autobody place in town and for $80 a side they are going to push the whole tire well back to eliminate any rubbing. They are also going to use a heat gun and bend the stock fender flares so that it doesn't look ghetto and retains a stock look. After the modifications are done then they are going to put some paint so that there isn't going to be a problem with rusting in the future.
Rubbing would also depend if you have aftermarket wheels with a different offset. On mine right now I'm still using the stock rims but I'm having the fender well cut enough so that I can run a different offset rim. I also have a 3" lift. Hope that helps.